STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mvkCOG1577 Mevalonate kinase. (302 aa)    
Predicted Functional Partners:
ADZ06801.1
COG1257 Hydroxymethylglutaryl-CoA reductase; Belongs to the HMG-CoA reductase family.
 0.999
ADZ07376.1
COG1577 Mevalonate kinase.
 
 
 0.997
ADZ07375.1
COG3407 Mevalonate pyrophosphate decarboxylase.
 
  
 0.995
fni
Isopentenyl pyrophosphate isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
 
  
 0.958
ADZ06802.1
COG3425 3-hydroxy-3-methylglutaryl CoA synthase.
 
  
 0.868
dinG
ATP-dependent DNA helicase; 3'-5' exonuclease.
 
     0.784
ADZ07370.1
COG5353 Uncharacterized protein conserved in bacteria.
       0.742
rexB
ATP-dependent exonuclease subunit B; ATP-dependent DNA helicase.
       0.677
addA
ATP-dependent helicase/nuclease subunit A; ATP-dependent DNA helicase.
       0.676
asnC
COG0017 Aspartyl/asparaginyl-tRNA synthetases.
  
    0.592
Your Current Organism:
Lactobacillus amylovorus
NCBI taxonomy Id: 1604
Other names: ATCC 33620, CCUG 27201, CIP 102989, DSM 16698 [[Lactobacillus sobrius]], DSM 20531, L. amylovorus, LMG 9496, LMG:9496, Lactobacillus acidophilus group A3, Lactobacillus sobrius, Lactobacillus sobrius Konstantinov et al. 2006, NCAIM B.01458, NCCB 100067 [[Lactobacillus sobrius]], NRRL B-4540, strain OTU171-001 [[Lactobacillus sobrius]]
Server load: low (26%) [HD]