STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
coaDPhosphopantetheine adenylyltransferase. (163 aa)    
Predicted Functional Partners:
ALG82844.1
Hypothetical protein; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).
  
  
 0.954
dfp
Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase.
    
 0.906
ALG81526.1
Hypothetical protein; Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
      0.770
ALG81090.1
Hypothetical protein.
  
     0.547
nop56/58
Nucleolar protein-like protein.
 
     0.502
eif6
Translation initiation factor IF-6; Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex.
  
     0.502
ALG82592.1
Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+).
  
    0.473
ALG81272.1
RNA-binding protein.
  
     0.467
flpA
Fibrillarin; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family.
 
     0.461
ALG82048.1
Serine/threonine protein kinase.
  
     0.457
Your Current Organism:
Halanaeroarchaeum sulfurireducens
NCBI taxonomy Id: 1604004
Other names: H. sulfurireducens, Halanaeroarchaeum sulfurireducens Sorokin et al. 2016, Halobacteriaceae archaeon HSR2, Halobacteriaceae archaeon HSR3, Halobacteriaceae archaeon HSR4, Halobacteriaceae archaeon HSR5, Halobacteriaceae archaeon HSR7, Halobacteriaceae archaeon M27-SA2, JCM 30661, UNIQEM U935, strain HSR2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.