STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OJG81454.1Hypothetical protein. (409 aa)    
Predicted Functional Partners:
OJG76376.1
drug:H+ antiporter-2 (14 Spanner) (DHA2) family drug resistance MFS transporter.
 
  
 0.711
OJG77131.1
Hypothetical protein.
 
  
0.681
OJG76932.1
drug:H+ antiporter-2 (14 Spanner) (DHA2) family drug resistance MFS transporter.
 
  
 0.674
OJG76632.1
drug:H+ antiporter-2 (14 Spanner) (DHA2) family drug resistance MFS transporter; Belongs to the major facilitator superfamily.
 
  
 0.674
tdk
Thymidine kinase.
    
  0.665
OJG80378.1
Ribonucleoside-diphosphate reductase, class 1b, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
    
  0.663
OJG78617.1
Hypothetical protein.
 
  
0.649
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
    
  0.638
tmk
Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
    
  0.638
OJG80377.1
Ribonucleoside-diphosphate reductase, class 1b, beta subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family.
    
  0.638
Your Current Organism:
Enterococcus pallens
NCBI taxonomy Id: 160454
Other names: ATCC BAA-351, CCUG 45554, E. pallens, Enterococcus pallens Tyrrell et al. 2002, NBRC 100697, strain PQ2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.