STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tag3-methyl-adenine DNA glycosylase I; Function of homologous gene experimentally demonstrated in an other organism; enzyme; DNAmetabolism : DNA replication, recombination, and repair. (183 aa)    
Predicted Functional Partners:
ogt
O6-methylguanine-DNA methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
   
 0.907
PP_4812
Putative 3-methyladenine DNA glycosylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the DNA glycosylase MPG family.
      
 0.822
imuB
DNA linked enzyme involved in DNA repair; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
     
 0.817
PP_0063
Putative Lipid A biosynthesis lauroyl acyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
  
 0.816
dinB
DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
 
   
 0.795
gmhB
D-glycero-beta-D-manno-heptose-1,7-bisphosphate 7-phosphatase; Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate (beta-HBP) intermediate into D-glycero-beta-D-manno-heptose 1-phosphate by removing the phosphate group at the C-7 position. Belongs to the gmhB family.
       0.758
glyS
glycine-tRNA ligase beta subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
       0.758
glyQ
glycine-tRNA ligase alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
       0.758
PP_0058
Putative 1-acyl-sn-glycerol-3-phosphate acyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
       0.709
guaA
Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP.
      0.698
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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