STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PP_0064Homologs of previously reported genes of unknown function. (104 aa)    
Predicted Functional Partners:
trkA
NAD-binding component of TrK potassium transporter; Function of homologous gene experimentally demonstrated in an other organism; transporter; Transportandbindingproteins : Cations and iron carrying compounds.
       0.797
rsmB
Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
       0.741
fmt
Methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.
       0.741
def-I
Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
  
   0.689
estP
Esterase EstP; Esterase that catalyzes the hydrolysis of p-nitrophenyl esters of acyl chain lengths C4-C10 and Tween detergents. Has also a pronounced thioesterase activity towards palmitoyl-coenzyme A. Belongs to the 'GDSL' lipolytic enzyme family.
 
   0.461
PP_3117
Putative protein involved in error-prone processing of DNA lesions; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor; DNAmetabolism : DNA replication, recombination, and repair.
  
     0.453
PP_1504
Homologs of previously reported genes of unknown function.
  
     0.428
imuB
DNA linked enzyme involved in DNA repair; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
     0.414
PP_1822
Homologs of previously reported genes of unknown function.
  
     0.409
PP_0069
Putative Rossmann fold nucleotide-binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor; Cellular processes.
  
    0.401
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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