Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
betCCholine-sulfatase; Function experimentally demonstrated in the studied strain; enzyme; Central intermediary metabolism. (505 aa)    
Predicted Functional Partners:
PP_0076
Putative choline betaine-binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
 
     0.799
PP_2814
Homologs of previously reported genes of unknown function.
  
     0.765
PP_2807
Homologs of previously reported genes of unknown function.
  
     0.711
PP_0079
Putative transcriptional regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator; Belongs to the LysR transcriptional regulatory family.
 
     0.673
betA-I
Choline dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
    
 0.660
betA-II
Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.
    
 0.660
pchP
Phosphoethanolamine/phosphocholine phosphatase; Function experimentally demonstrated in the studied genus; enzyme; Biologicalprocesses : Scavenge (Catabolism).
 
     0.657
PP_3353
Putative sulfatase-modifying factor (C-alpha-formyglycine- generating enzyme); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Unknownfunction : Enzymes of unknown specificity.
 
   0.613
PP_0081
Homologs of previously reported genes of unknown function.
 
     0.611
pvdO
Pyoverdine biosynthesis related protein; Function of strongly homologous gene; enzyme; Fattyacidandphospholipidmetabolism : Biosynthesis.
 
   0.556
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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