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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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[Homology]
Score
PP_0088Putative alkanal monooxygenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (334 aa)    
Predicted Functional Partners:
ethA
FAD-containing monooxygenase EthA; Catalyzes a Baeyer-Villiger oxidation reaction, i.e. the insertion of an oxygen atom into a carbon-carbon bond adjacent to a carbonyl, which converts ketones to esters or lactones using NADPH and/or NADH as an electron donor. Preferentially converts short-chain aliphatic ketones like 2-decanone, 3-decanone and 4-decanone. Some acyclic ketones are converted not only to the alkylacetates, but also methyl- and ethylesters are obtained, indicating insertion of oxygen on both sides of the keto group; Belongs to the FAD-binding monooxygenase family.
     
 0.713
osmC
Stress-induced peroxiredoxin, lipoyl-dependent peroxidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Cellularprocesses : Adaptations to atypical conditions.
       0.608
PP_0090
Homologs of previously reported genes of unknown function.
       0.595
PP_3926
Short-chain dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Biologicalprocesses : Scavenge (Catabolism).
      
 0.524
fdhA
Formaldehyde dehydrogenase; Function experimentally demonstrated in the studied species; enzyme; Energy metabolism.
      
 0.464
glyA-I
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
      
 0.408
glyA-II
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
      
 0.403
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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