Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
katEHydroperoxidase - self catalytic heme d synthase; Serves to protect cells from the toxic effects of hydrogen peroxide. (711 aa)    
Predicted Functional Partners:
katG
Catalase-peroxidase; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily.
    
 0.989
PP_2887
Catalase-related peroxidase; Has an organic peroxide-dependent peroxidase activity. Belongs to the catalase family.
  
  
0.942
sodA
Superoxide dismutase (Mn); Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
  
 0.932
katA
Catalase; Belongs to the catalase family.
  
  
 
0.909
sodB
Superoxide dismutase (Fe); Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the iron/manganese superoxide dismutase family.
  
 0.904
ahpF
Alkyl hydroperoxide reductase subunit F; Serves to protect the cell against DNA damage by alkyl hydroperoxides. It can use either NADH or NADPH as electron donor for direct reduction of redox dyes or of alkyl hydroperoxides when combined with the AhpC protein (By similarity); Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
  
  
 0.880
oxyR
Oxidative and nitrosative stress transcriptional dual regulator; Function of homologous gene experimentally demonstrated in an other organism; regulator; Transcription; Belongs to the LysR transcriptional regulatory family.
     
 0.768
osmC
Stress-induced peroxiredoxin, lipoyl-dependent peroxidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Cellularprocesses : Adaptations to atypical conditions.
  
  
 0.766
ahpC
Peroxiredoxin, alkylhydroperoxide reductase - small subunit; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
  
 
 0.757
paaZ
oxepin-CoA hydrolase/3-oxo-5,6-dehydrosuberyl-CoA semialdehyde dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energy metabolism.
   
 0.679
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
Server load: low (18%) [HD]