Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PP_0175Putative transcriptional regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. (150 aa)    
Predicted Functional Partners:
PP_0176
Putative efflux transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
 
  
 0.946
PP_0178
Putative efflux pump; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
  
 0.914
PP_0177
Homologs of previously reported genes of unknown function.
       0.869
PP_0179
Putative efflux transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
 
    0.820
PP_2161
Homologs of previously reported genes of unknown function.
      
 0.813
PP_1135
Homologs of previously reported genes of unknown function.
      
 0.768
pepN
Function of homologous gene experimentally demonstrated in an other organism; enzyme; Proteinfate : Degradation of proteins, peptides, and glycopeptides.
      
 0.750
PP_1150
Putative Membrane protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
   
 0.667
hisG
ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
      
 0.666
hemF
Coproporphyrinogen-III oxidase, aerobic; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX.
      
 0.656
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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