| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| algB | algC | PP_0133 | PP_5288 | Alginate biosynthesis transcriptional regulatory protein AlgB; Positive regulator of the alginate biosynthetic gene algD. | Phosphomannomutase/phosphoglucomutase; The phosphomannomutase activity produces a precursor for alginate polymerization. The alginate layer causes a mucoid phenotype and provides a protective barrier against host immune defenses and antibiotics. Also involved in core-LPS biosynthesis due to its phosphoglucomutase activity. Essential for biofilm production (By similarity). | 0.648 |
| algB | algD | PP_0133 | PP_1288 | Alginate biosynthesis transcriptional regulatory protein AlgB; Positive regulator of the alginate biosynthetic gene algD. | GDP-mannose 6-dehydrogenase; Catalyzes the oxidation of guanosine diphospho-D-mannose (GDP-D-mannose) to GDP-D-mannuronic acid, a precursor for alginate polymerization. The alginate layer causes a mucoid phenotype and provides a protective barrier against host immune defenses and antibiotics (By similarity). | 0.738 |
| algB | algP | PP_0133 | PP_0194 | Alginate biosynthesis transcriptional regulatory protein AlgB; Positive regulator of the alginate biosynthetic gene algD. | Transcriptional regulatory protein AlgP. | 0.738 |
| algB | algQ | PP_0133 | PP_0191 | Alginate biosynthesis transcriptional regulatory protein AlgB; Positive regulator of the alginate biosynthetic gene algD. | Transcriptional regulatory protein AlgQ; Belongs to the Rsd/AlgQ family. | 0.647 |
| algB | algR | PP_0133 | PP_0185 | Alginate biosynthesis transcriptional regulatory protein AlgB; Positive regulator of the alginate biosynthetic gene algD. | Positive alginate biosynthesis regulatory protein. | 0.834 |
| algB | kinB | PP_0133 | PP_0132 | Alginate biosynthesis transcriptional regulatory protein AlgB; Positive regulator of the alginate biosynthetic gene algD. | Alginate biosynthesis sensor protein KinB. | 0.998 |
| algB | mucA | PP_0133 | PP_1428 | Alginate biosynthesis transcriptional regulatory protein AlgB; Positive regulator of the alginate biosynthetic gene algD. | Sigma factor AlgU negative regulatory protein. | 0.751 |
| algB | mucB | PP_0133 | PP_1429 | Alginate biosynthesis transcriptional regulatory protein AlgB; Positive regulator of the alginate biosynthetic gene algD. | Sigma factor AlgU regulatory protein MucB. | 0.744 |
| algC | algB | PP_5288 | PP_0133 | Phosphomannomutase/phosphoglucomutase; The phosphomannomutase activity produces a precursor for alginate polymerization. The alginate layer causes a mucoid phenotype and provides a protective barrier against host immune defenses and antibiotics. Also involved in core-LPS biosynthesis due to its phosphoglucomutase activity. Essential for biofilm production (By similarity). | Alginate biosynthesis transcriptional regulatory protein AlgB; Positive regulator of the alginate biosynthetic gene algD. | 0.648 |
| algC | algD | PP_5288 | PP_1288 | Phosphomannomutase/phosphoglucomutase; The phosphomannomutase activity produces a precursor for alginate polymerization. The alginate layer causes a mucoid phenotype and provides a protective barrier against host immune defenses and antibiotics. Also involved in core-LPS biosynthesis due to its phosphoglucomutase activity. Essential for biofilm production (By similarity). | GDP-mannose 6-dehydrogenase; Catalyzes the oxidation of guanosine diphospho-D-mannose (GDP-D-mannose) to GDP-D-mannuronic acid, a precursor for alginate polymerization. The alginate layer causes a mucoid phenotype and provides a protective barrier against host immune defenses and antibiotics (By similarity). | 0.888 |
| algC | algP | PP_5288 | PP_0194 | Phosphomannomutase/phosphoglucomutase; The phosphomannomutase activity produces a precursor for alginate polymerization. The alginate layer causes a mucoid phenotype and provides a protective barrier against host immune defenses and antibiotics. Also involved in core-LPS biosynthesis due to its phosphoglucomutase activity. Essential for biofilm production (By similarity). | Transcriptional regulatory protein AlgP. | 0.434 |
| algC | algQ | PP_5288 | PP_0191 | Phosphomannomutase/phosphoglucomutase; The phosphomannomutase activity produces a precursor for alginate polymerization. The alginate layer causes a mucoid phenotype and provides a protective barrier against host immune defenses and antibiotics. Also involved in core-LPS biosynthesis due to its phosphoglucomutase activity. Essential for biofilm production (By similarity). | Transcriptional regulatory protein AlgQ; Belongs to the Rsd/AlgQ family. | 0.435 |
| algC | algR | PP_5288 | PP_0185 | Phosphomannomutase/phosphoglucomutase; The phosphomannomutase activity produces a precursor for alginate polymerization. The alginate layer causes a mucoid phenotype and provides a protective barrier against host immune defenses and antibiotics. Also involved in core-LPS biosynthesis due to its phosphoglucomutase activity. Essential for biofilm production (By similarity). | Positive alginate biosynthesis regulatory protein. | 0.855 |
| algC | kinB | PP_5288 | PP_0132 | Phosphomannomutase/phosphoglucomutase; The phosphomannomutase activity produces a precursor for alginate polymerization. The alginate layer causes a mucoid phenotype and provides a protective barrier against host immune defenses and antibiotics. Also involved in core-LPS biosynthesis due to its phosphoglucomutase activity. Essential for biofilm production (By similarity). | Alginate biosynthesis sensor protein KinB. | 0.527 |
| algC | mucA | PP_5288 | PP_1428 | Phosphomannomutase/phosphoglucomutase; The phosphomannomutase activity produces a precursor for alginate polymerization. The alginate layer causes a mucoid phenotype and provides a protective barrier against host immune defenses and antibiotics. Also involved in core-LPS biosynthesis due to its phosphoglucomutase activity. Essential for biofilm production (By similarity). | Sigma factor AlgU negative regulatory protein. | 0.735 |
| algC | mucB | PP_5288 | PP_1429 | Phosphomannomutase/phosphoglucomutase; The phosphomannomutase activity produces a precursor for alginate polymerization. The alginate layer causes a mucoid phenotype and provides a protective barrier against host immune defenses and antibiotics. Also involved in core-LPS biosynthesis due to its phosphoglucomutase activity. Essential for biofilm production (By similarity). | Sigma factor AlgU regulatory protein MucB. | 0.763 |
| algD | algB | PP_1288 | PP_0133 | GDP-mannose 6-dehydrogenase; Catalyzes the oxidation of guanosine diphospho-D-mannose (GDP-D-mannose) to GDP-D-mannuronic acid, a precursor for alginate polymerization. The alginate layer causes a mucoid phenotype and provides a protective barrier against host immune defenses and antibiotics (By similarity). | Alginate biosynthesis transcriptional regulatory protein AlgB; Positive regulator of the alginate biosynthetic gene algD. | 0.738 |
| algD | algC | PP_1288 | PP_5288 | GDP-mannose 6-dehydrogenase; Catalyzes the oxidation of guanosine diphospho-D-mannose (GDP-D-mannose) to GDP-D-mannuronic acid, a precursor for alginate polymerization. The alginate layer causes a mucoid phenotype and provides a protective barrier against host immune defenses and antibiotics (By similarity). | Phosphomannomutase/phosphoglucomutase; The phosphomannomutase activity produces a precursor for alginate polymerization. The alginate layer causes a mucoid phenotype and provides a protective barrier against host immune defenses and antibiotics. Also involved in core-LPS biosynthesis due to its phosphoglucomutase activity. Essential for biofilm production (By similarity). | 0.888 |
| algD | algP | PP_1288 | PP_0194 | GDP-mannose 6-dehydrogenase; Catalyzes the oxidation of guanosine diphospho-D-mannose (GDP-D-mannose) to GDP-D-mannuronic acid, a precursor for alginate polymerization. The alginate layer causes a mucoid phenotype and provides a protective barrier against host immune defenses and antibiotics (By similarity). | Transcriptional regulatory protein AlgP. | 0.703 |
| algD | algQ | PP_1288 | PP_0191 | GDP-mannose 6-dehydrogenase; Catalyzes the oxidation of guanosine diphospho-D-mannose (GDP-D-mannose) to GDP-D-mannuronic acid, a precursor for alginate polymerization. The alginate layer causes a mucoid phenotype and provides a protective barrier against host immune defenses and antibiotics (By similarity). | Transcriptional regulatory protein AlgQ; Belongs to the Rsd/AlgQ family. | 0.642 |