Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
algQTranscriptional regulatory protein AlgQ; Belongs to the Rsd/AlgQ family. (156 aa)    
Predicted Functional Partners:
rpoD
RNA polymerase, sigma 70 (sigma D) factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
   
 
 0.961
algP
Transcriptional regulatory protein AlgP.
  
  
 0.924
algR
Positive alginate biosynthesis regulatory protein.
  
  
 0.860
rpoS
RNA polymerase, sigma S (sigma 38) factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.
  
 
 0.784
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
     
 0.762
yohC
Putative inner membrane protein of unknown function; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative membrane component; Transport and binding proteins.
  
    0.758
hemD
Uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
 
   
 0.711
PP_4918
Homologs of previously reported genes of unknown function.
  
     0.705
dsbB2
Putative disulfide bond formation protein B; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity). Belongs to the DsbB family.
       0.695
PP_0189
Putative heme biosynthesis protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Biosynthesisofcofactors,prostheticgroups,andcarriers : Heme, porphyrin, and cobalamin.
 
   
 0.666
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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