Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
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[Homology]
Score
algPTranscriptional regulatory protein AlgP. (329 aa)    
Predicted Functional Partners:
algQ
Transcriptional regulatory protein AlgQ; Belongs to the Rsd/AlgQ family.
  
  
 0.924
algR
Positive alginate biosynthesis regulatory protein.
  
  
 0.829
algB
Alginate biosynthesis transcriptional regulatory protein AlgB; Positive regulator of the alginate biosynthetic gene algD.
      
 0.758
fkl
Putative FKBP-type 25 kDa peptidyl-prolyl cis-trans isomerase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
       0.744
algD
GDP-mannose 6-dehydrogenase; Catalyzes the oxidation of guanosine diphospho-D-mannose (GDP-D-mannose) to GDP-D-mannuronic acid, a precursor for alginate polymerization. The alginate layer causes a mucoid phenotype and provides a protective barrier against host immune defenses and antibiotics (By similarity).
      
 0.708
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
  
 0.569
mucB
Sigma factor AlgU regulatory protein MucB.
      
 0.561
mucA
Sigma factor AlgU negative regulatory protein.
      
 0.542
kinB
Alginate biosynthesis sensor protein KinB.
     
 0.536
hemD
Uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
     
 0.514
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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