STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
algPTranscriptional regulatory protein AlgP. (329 aa)    
Predicted Functional Partners:
algQ
Transcriptional regulatory protein AlgQ; Belongs to the Rsd/AlgQ family.
  
  
 0.848
algR
Positive alginate biosynthesis regulatory protein.
  
  
 0.842
algB
Alginate biosynthesis transcriptional regulatory protein AlgB; Positive regulator of the alginate biosynthetic gene algD.
      
 0.738
algD
GDP-mannose 6-dehydrogenase; Catalyzes the oxidation of guanosine diphospho-D-mannose (GDP-D-mannose) to GDP-D-mannuronic acid, a precursor for alginate polymerization. The alginate layer causes a mucoid phenotype and provides a protective barrier against host immune defenses and antibiotics (By similarity).
      
 0.703
hemD
Uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
  
  
 0.618
fkl
Putative FKBP-type 25 kDa peptidyl-prolyl cis-trans isomerase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
    0.594
PP_4924
Serine protease, subtilase family.
  
  
 0.558
mucB
Sigma factor AlgU regulatory protein MucB.
      
 0.518
kinB
Alginate biosynthesis sensor protein KinB.
     
 0.512
mucA
Sigma factor AlgU negative regulatory protein.
   
  
 0.511
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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