Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PP_0197Homologs of previously reported genes of unknown function. (195 aa)    
Predicted Functional Partners:
yheS
Putative of ABC superfamily informational factor: ATP-binding components; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative cell process; Transport and binding proteins.
  
    0.904
PP_0195
Homologs of previously reported genes of unknown function.
       0.763
PP_0198
Putative transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
       0.746
PP_4707
OsmY-related protein.
  
     0.554
PP_0180
Putative cytochrome c family protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
 
     0.550
PP_5221
Conserved protein of unknown function, UPF0178 family; Homologs of previously reported genes of unknown function; Unknown function; Belongs to the UPF0178 family.
       0.488
PP_5432
Homologs of previously reported genes of unknown function; Unknown function.
  
     0.463
PP_1357
Homologs of previously reported genes of unknown function; Unknown function.
 
     0.448
gcvP-I
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein (By similarity); Belongs to the GcvP family.
   
    0.418
gcvP-II
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein (By similarity); Belongs to the GcvP family.
   
    0.418
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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