STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nfeDPutative membrane bound peptidase, nefD; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Regulatory functions. (448 aa)    
Predicted Functional Partners:
qmcA
Putative membrane protease family, stomatin; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Proteinfate : Degradation of proteins, peptides, and glycopeptides.
 
  
 0.967
lon-I
DNA-binding, ATP-dependent protease; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
  
  
 0.853
lon-II
DNA-binding, ATP-dependent protease; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
     
 0.848
PP_0201
Homologs of previously reported genes of unknown function.
 
     0.759
PP_4834
SPFH domain/Band 7 family protein.
 
  
 0.554
PP_4833
SURF1 domain protein.
  
  
 0.544
hflC
Integral membrane ATP-dependent zinc metallopeptidase / HflK-HflC complex; HflC and HflK could regulate a protease.
 
  
 0.458
PP_5432
Homologs of previously reported genes of unknown function; Unknown function.
       0.458
hflK
Integral membrane ATP-dependent zinc metallopeptidase / HflK-HflC complex; HflC and HflK could encode or regulate a protease.
 
  
 0.420
PP_3231
Homologs of previously reported genes of unknown function.
  
  
 0.407
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.