Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
yhgFPutative transcriptional accessory protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor; Transcription. (861 aa)    
Predicted Functional Partners:
PP_0244
Homologs of previously reported genes of unknown function.
  
    0.887
yadH
Putative ABC transporter - permease subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Transport and binding proteins.
      
 0.865
fusB
Elongation factor G 2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
   
  
 0.852
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.776
dmoA-II
Dimethyl-sulfide monooxygenase; Function of strongly homologous gene; enzyme; Central intermediary metabolism.
     
 0.771
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.767
PP_3534
Transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.
      
 0.767
aruH
Arginine--pyruvate transaminase AruH.
      
 0.741
PP_3363
Putative thymidylate kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Purines, pyrimidines, nucleosides, and nucleotides.
      
 0.720
gshA
Glutamate--cysteine ligase; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
       0.719
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.