| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PP_0249 | rimK | PP_0249 | PP_0248 | Homologs of previously reported genes of unknown function. | Probable alpha-L-glutamate ligase. | 0.996 |
| PP_0333 | rimK | PP_0333 | PP_0248 | Homologs of previously reported genes of unknown function. | Probable alpha-L-glutamate ligase. | 0.776 |
| PP_2332 | rimK | PP_2332 | PP_0248 | Homologs of previously reported genes of unknown function. | Probable alpha-L-glutamate ligase. | 0.773 |
| PP_3253 | purT | PP_3253 | PP_1457 | Carboxylate-amine ligase PP_3253; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily. | Phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. | 0.404 |
| PP_3253 | rimK | PP_3253 | PP_0248 | Carboxylate-amine ligase PP_3253; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily. | Probable alpha-L-glutamate ligase. | 0.791 |
| ddl | purT | PP_5673 | PP_1457 | Putative D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | Phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. | 0.649 |
| ddl | rimK | PP_5673 | PP_0248 | Putative D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | Probable alpha-L-glutamate ligase. | 0.691 |
| gbcA | rimK | PP_0315 | PP_0248 | Putative glycine-betaine dioxygenase subunit; Function experimentally demonstrated in the studied genus; putative enzyme; Fattyacidandphospholipidmetabolism : Degradation. | Probable alpha-L-glutamate ligase. | 0.766 |
| hfq | rimK | PP_4894 | PP_0248 | RNA-binding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | Probable alpha-L-glutamate ligase. | 0.754 |
| hfq | rpsF | PP_4894 | PP_4877 | RNA-binding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA. | 0.697 |
| purT | PP_3253 | PP_1457 | PP_3253 | Phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. | Carboxylate-amine ligase PP_3253; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily. | 0.404 |
| purT | ddl | PP_1457 | PP_5673 | Phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. | Putative D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | 0.649 |
| purT | rimK | PP_1457 | PP_0248 | Phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. | Probable alpha-L-glutamate ligase. | 0.716 |
| rimK | PP_0249 | PP_0248 | PP_0249 | Probable alpha-L-glutamate ligase. | Homologs of previously reported genes of unknown function. | 0.996 |
| rimK | PP_0333 | PP_0248 | PP_0333 | Probable alpha-L-glutamate ligase. | Homologs of previously reported genes of unknown function. | 0.776 |
| rimK | PP_2332 | PP_0248 | PP_2332 | Probable alpha-L-glutamate ligase. | Homologs of previously reported genes of unknown function. | 0.773 |
| rimK | PP_3253 | PP_0248 | PP_3253 | Probable alpha-L-glutamate ligase. | Carboxylate-amine ligase PP_3253; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily. | 0.791 |
| rimK | ddl | PP_0248 | PP_5673 | Probable alpha-L-glutamate ligase. | Putative D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | 0.691 |
| rimK | gbcA | PP_0248 | PP_0315 | Probable alpha-L-glutamate ligase. | Putative glycine-betaine dioxygenase subunit; Function experimentally demonstrated in the studied genus; putative enzyme; Fattyacidandphospholipidmetabolism : Degradation. | 0.766 |
| rimK | hfq | PP_0248 | PP_4894 | Probable alpha-L-glutamate ligase. | RNA-binding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 0.754 |