Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PP_0251Homologs of previously reported genes of unknown function. (264 aa)    
Predicted Functional Partners:
hslO
33 kDa chaperonin; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
  
  
 0.773
PP_1357
Homologs of previously reported genes of unknown function; Unknown function.
  
     0.675
lptE
Putative Lipoprotein; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane; Belongs to the LptE lipoprotein family.
  
     0.672
phoQ
Sensor protein; Function of homologous gene experimentally demonstrated in an other organism; regulator; Transcription.
  
   
 0.652
hslR
Heat shock protein Hsp15 involved in ribosome recycling; Function of homologous gene experimentally demonstrated in an other organism; factor; Cellularprocesses : Adaptations to atypical conditions; Belongs to the HSP15 family.
      
 0.584
PP_2565
Putative helicase, UvrD/REP family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; DNA metabolism.
  
     0.548
PP_0693
Homologs of previously reported genes of unknown function.
  
     0.515
PP_4775
Homologs of previously reported genes of unknown function; Unknown function.
  
     0.502
gloA
Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.
      
 0.484
PP_4923
Outer membrane efflux protein.
  
     0.484
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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