Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
dctD-IC4-dicarboxylate transport transcriptional regulatory protein; Function of strongly homologous gene; regulator. (468 aa)    
Predicted Functional Partners:
PP_0264
Sensor histidine kinase.
 0.994
dctB
C4-dicarboxylate transport sensor protein.
 
 0.974
dctD-III
C4-dicarboxylate transport transcriptional regulatory protein; Function of strongly homologous gene; regulator.
  
  
 
0.903
rpoN
RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of the xylCAB operon and the xylS gene. The open complex (sigma-54 and core RNA polymerase) serves as the receptor for receipt of the melting signal from the remotely bound activator protein XylR for the expression of the xylCAB operon and xylS.
 
   
 0.792
PP_0262
Homologs of previously reported genes of unknown function.
       0.773
PP_1067
Sensor histidine kinase.
 
 0.696
rmlC
dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
     
 0.662
glnL
Two-component system sensory histidine kinase/phosphatase GlnL/GlnG; Function of homologous gene experimentally demonstrated in an other organism; receptor; Centralintermediarymetabolism : Nitrogen metabolism.
 
 0.612
PP_4959
Diguanylate cyclase; Function of strongly homologous gene; enzyme.
  
 
 0.604
PP_4342
Flagellar synthesis regulator, putative ATPase; Function of homologous gene experimentally demonstrated in an other organism; regulator.
  
 
 0.575
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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