Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PP_0264Sensor histidine kinase. (604 aa)    
Predicted Functional Partners:
dctD-I
C4-dicarboxylate transport transcriptional regulatory protein; Function of strongly homologous gene; regulator.
 0.994
dctD-III
C4-dicarboxylate transport transcriptional regulatory protein; Function of strongly homologous gene; regulator.
 0.977
dctB
C4-dicarboxylate transport sensor protein.
  
  
 
0.921
PP_0262
Homologs of previously reported genes of unknown function.
       0.869
rmlC
dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
   
   0.812
dctD-II
C4-dicarboxylate transport transcriptional regulatory protein; Function of strongly homologous gene; regulator.
 
 0.749
PP_2683
Putative sensory box histidine kinase/response regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
 
 0.689
PP_3761
Sensor histidine kinase/response regulator.
  
 
 0.494
rffG
dTDP-glucose 4,6-dehydratase 2; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Cellenvelope : Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
     
 0.491
rfbA
dTDP-glucose pyrophosphorylase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.
       0.488
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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