STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mutYAdenine glycosylase; Adenine glycosylase active on G-A mispairs. (355 aa)    
Predicted Functional Partners:
sfsA
Sugar fermentation stimulation protein A; Function of homologous gene experimentally demonstrated in an other organism; regulator; Energy metabolism; Belongs to the SfsA family.
 
    0.935
mutM
Formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
  
  
 0.911
PP_0285
Fe(2+)-trafficking protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
  
  
 0.830
PP_0287
Homologs of previously reported genes of unknown function.
  
    0.813
mutL
DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
 
   
 0.806
xthA
Exodeoxyribonuclease III / apurinic/apyrimidinic endodeoxyribonuclease VI; Function of homologous gene experimentally demonstrated in an other organism; enzyme; DNAmetabolism : Degradation of DNA.
  
 0.708
PP_5292
Catabolite repression control protein.
  
 
 0.699
PP_2707
Putative Exodeoxyribonuclease III; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
 
 0.689
pfpI
Protease PfpI.
     
 0.679
uvrD
DNA-dependent ATPase I and helicase II, nucleotide Excision Repair Complex; Function of homologous gene experimentally demonstrated in an other organism; enzyme; DNAmetabolism : DNA replication, recombination, and repair.
      
 0.668
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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