STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PP_0288Putative Oxalate/formate antiporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (553 aa)    
Predicted Functional Partners:
hisB
Imidazoleglycerol-phosphate dehydratase.
      0.870
hisA
Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide isomerase; Function of strongly homologous gene; enzyme; Aminoacidbiosynthesis : Histidine family.
      0.778
PP_3582
RND efflux transporter, outer membrane protein.
   
 
 0.765
PP_2186
Putative Formate dehydrogenase, delta subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
   
 0.734
hisH
Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
       0.709
PP_0291
Homologs of previously reported genes of unknown function.
       0.709
ccoP-II
Cytochrome c oxidase subunit, cbb3-type; C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
      
 0.655
sahR
Transcriptional regulator of methionine metabolism; Function of homologous gene experimentally demonstrated in an other organism; regulator.
     
 0.648
PP_2185
Putative Formate dehydrogenase, alpha subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
     0.634
fdhD
Protein sulfur transferase; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family.
 
  
 0.524
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.