Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PP_0354CBS domain protein. (645 aa)    
Predicted Functional Partners:
PP_0353
Exonuclease.
 
  
 0.992
yjcH
Conserved inner membrane protein of unknown function; Homologs of previously reported genes of unknown function; putative membrane component; Unknown function.
 
  
 0.959
actP-I
Acetate permease; Function of homologous gene experimentally demonstrated in an other organism; transporter; Transportandbindingproteins : Carbohydrates, organic alcohols, and acids; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
 
  
 0.959
actP-II
Acetate permease; Function of homologous gene experimentally demonstrated in an other organism; transporter; Transportandbindingproteins : Carbohydrates, organic alcohols, and acids; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
 
  
 0.933
actP-III
Acetate permease; Function of homologous gene experimentally demonstrated in an other organism; transporter; Transportandbindingproteins : Carbohydrates, organic alcohols, and acids; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
 
  
 0.930
scpC
propionyl-CoA:succinate CoA transferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Central intermediary metabolism.
  
  
 0.889
rnt
Ribonuclease T; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.
  
  
 0.793
acs
Butyrate--CoA ligase; Function experimentally demonstrated in the studied genus; enzyme; Fatty acid and phospholipid metabolism.
      
 0.718
PP_1635
DNA-binding response regulator.
   
  
 0.670
acsA-I
acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
  
 0.622
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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