| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PP_0358 | PP_0361 | PP_0358 | PP_0361 | Homologs of previously reported genes of unknown function. | Putative Competence protein ComF; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | 0.428 |
| PP_0358 | modR | PP_0358 | PP_0360 | Homologs of previously reported genes of unknown function. | Molybdate transport regulator. | 0.486 |
| PP_0358 | rdoA | PP_0358 | PP_0359 | Homologs of previously reported genes of unknown function. | Serine/threonine protein kinase; A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response. | 0.612 |
| PP_0361 | PP_0358 | PP_0361 | PP_0358 | Putative Competence protein ComF; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Homologs of previously reported genes of unknown function. | 0.428 |
| PP_0361 | bioB | PP_0361 | PP_0362 | Putative Competence protein ComF; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.649 |
| PP_0361 | bioC | PP_0361 | PP_0365 | Putative Competence protein ComF; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Malonyl-[acyl-carrier protein] O-methyltransferase; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. | 0.648 |
| PP_0361 | bioD | PP_0361 | PP_0366 | Putative Competence protein ComF; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.608 |
| PP_0361 | bioF | PP_0361 | PP_0363 | Putative Competence protein ComF; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.617 |
| PP_0361 | bioH | PP_0361 | PP_0364 | Putative Competence protein ComF; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Pimeloyl-[acp] methyl ester esterase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Biosynthesisofcofactors,prostheticgroups,andcarriers : Biotin. | 0.623 |
| PP_0361 | modR | PP_0361 | PP_0360 | Putative Competence protein ComF; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Molybdate transport regulator. | 0.696 |
| PP_0361 | rdoA | PP_0361 | PP_0359 | Putative Competence protein ComF; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Serine/threonine protein kinase; A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response. | 0.588 |
| asd | rdoA | PP_1989 | PP_0359 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Serine/threonine protein kinase; A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response. | 0.422 |
| bioB | PP_0361 | PP_0362 | PP_0361 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Putative Competence protein ComF; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | 0.649 |
| bioB | bioC | PP_0362 | PP_0365 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Malonyl-[acyl-carrier protein] O-methyltransferase; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. | 0.981 |
| bioB | bioD | PP_0362 | PP_0366 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.999 |
| bioB | bioF | PP_0362 | PP_0363 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.995 |
| bioB | bioH | PP_0362 | PP_0364 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Pimeloyl-[acp] methyl ester esterase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Biosynthesisofcofactors,prostheticgroups,andcarriers : Biotin. | 0.886 |
| bioB | modR | PP_0362 | PP_0360 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Molybdate transport regulator. | 0.555 |
| bioB | rdoA | PP_0362 | PP_0359 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Serine/threonine protein kinase; A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response. | 0.454 |
| bioC | PP_0361 | PP_0365 | PP_0361 | Malonyl-[acyl-carrier protein] O-methyltransferase; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. | Putative Competence protein ComF; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | 0.648 |