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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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PP_0375Prolyl oligopeptidase family protein. (612 aa)    
Predicted Functional Partners:
pqqC
Pyrroloquinoline-quinone synthase; Ring cyclization and eight-electron oxidation of 3a-(2-amino- 2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9- dicarboxylic-acid to PQQ.
  
  
 0.935
pqqB
Coenzyme PQQ synthesis protein B; May be involved in the transport of PQQ or its precursor to the periplasm; Belongs to the PqqB family.
  
  
 0.928
pqqE
Coenzyme PQQ synthesis protein E; Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).
  
  
 0.926
pqqD-I
Coenzyme PQQ synthesis protein D; Functions as a PqqA binding protein and presents PqqA to PqqE, in the pyrroloquinoline quinone (PQQ) biosynthetic pathway.
  
  
 0.887
pqqF
Coenzyme PQQ synthesis protein F; Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis. It is thought that this protein is a protease that cleaves peptides bond in a small peptide (gene pqqA), providing the glutamate and tyrosine residues which are necessary for the synthesis of PQQ (By similarity).
  
  
 0.823
PP_2683
Putative sensory box histidine kinase/response regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
  
  
 0.818
PP_2662
Homologs of previously reported genes of unknown function.
  
  
 0.815
PP_2736
Homologs of previously reported genes of unknown function.
      
 0.747
PP_2738
Putative Transcriptional regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
     
 0.747
yiaY
Fe-containing alcohol dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme; Central intermediary metabolism.
     
 0.665
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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