Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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pqqFCoenzyme PQQ synthesis protein F; Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis. It is thought that this protein is a protease that cleaves peptides bond in a small peptide (gene pqqA), providing the glutamate and tyrosine residues which are necessary for the synthesis of PQQ (By similarity). (766 aa)    
Predicted Functional Partners:
pqqB
Coenzyme PQQ synthesis protein B; May be involved in the transport of PQQ or its precursor to the periplasm; Belongs to the PqqB family.
     
 0.959
pqqE
Coenzyme PQQ synthesis protein E; Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).
     
 0.950
pqqC
Pyrroloquinoline-quinone synthase; Ring cyclization and eight-electron oxidation of 3a-(2-amino- 2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9- dicarboxylic-acid to PQQ.
     
 0.944
PP_0375
Prolyl oligopeptidase family protein.
  
  
 0.823
mpl
UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily.
    
   0.809
pqqD-I
Coenzyme PQQ synthesis protein D; Functions as a PqqA binding protein and presents PqqA to PqqE, in the pyrroloquinoline quinone (PQQ) biosynthetic pathway.
     
 0.717
davB
Lysine 2-monooxygenase; Function experimentally demonstrated in the studied strain; enzyme; Energymetabolism : Amino acids and amines.
       0.717
pqqD-II
Coenzyme PQQ synthesis protein D; Functions as a PqqA binding protein and presents PqqA to PqqE, in the pyrroloquinoline quinone (PQQ) biosynthetic pathway.
     
 0.639
pvdH
Diaminobutyrate-2-oxoglutarate transaminase; Function experimentally demonstrated in the studied genus; enzyme; Fattyacidandphospholipidmetabolism : Biosynthesis; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
      
 0.634
davA
5-aminopentanamidase; Function experimentally demonstrated in the studied strain; enzyme; Energymetabolism : Amino acids and amines.
   
   0.577
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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