STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yeaGProtein kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Unknown function. (640 aa)    
Predicted Functional Partners:
PP_0396
Homologs of previously reported genes of unknown function; Unknown function; Belongs to the UPF0229 family.
  
 0.999
ycgB
Putative type IV piliation protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; cell process; Unknown function.
 
  
 0.996
cca
tRNA nucleotidyltransferase - 2',3'-cyclic phosphodiesterase - 2' nucleotidase and phosphatase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
     
 0.854
yphA
Inner membrane protein of unknown function; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative membrane component; Unknown function.
   
  
 0.826
PP_2105
Homologs of previously reported genes of unknown function.
   
    0.781
dps
DNA-binding stress protein; Function experimentally demonstrated in the studied species; enzyme; DNAmetabolism : Chromosome-associated proteins; Belongs to the Dps family.
   
    0.738
PP_0085
Homologs of previously reported genes of unknown function.
   
    0.730
PP_4969
Homologs of previously reported genes of unknown function.
   
    0.712
glpE
Thiosulfate sulfurtransferase GlpE; Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.
  
    0.687
apaG
CO2+/MG2+ efflux protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Transport and binding proteins.
       0.679
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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