Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PP_0408Homologs of previously reported genes of unknown function. (332 aa)    
Predicted Functional Partners:
PP_4333
CheW domain protein.
  
     0.767
PP_5077
Homologs of previously reported genes of unknown function.
  
     0.757
ycgR
Flagellar brake protein YcgR; Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-dependent manner. Increasing levels of c-di-GMP lead to decreased motility (By similarity). Binds c-di-GMP with a dissociation constant of 165 nM. Binds 2 intercalated (c-di-GMP) dimers per subunit.
  
    0.752
PP_5209
Conserved exported protein of unknown function; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.
  
    0.746
PP_5126
Conserved protein of unknown function containing an HDOD domain; Homologs of previously reported genes of unknown function; Unknown function.
  
     0.736
PP_4331
Homologs of previously reported genes of unknown function.
  
     0.735
PP_5324
Response regulator.
  
     0.734
fleS
Sensory box histidine kinase FleS.
  
     0.730
PP_5311
Putative signal transduction protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor; Signal transduction.
  
     0.709
flgM
Negative regulator of flagellin synthesis FlgM.
  
     0.695
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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