yhfA protein (Pseudomonas putida KT2440) - STRING interaction network

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[Homology]

Score

yhfA

Homologs of previously reported genes of unknown function; Unknown function. (140 aa)

Predicted Functional Partners:

crp

0.745

ffh

0.727

ttgB

0.472

dsbA

0.445

hisG

0.416

ilvE

0.408

Your Current Organism:

Pseudomonas putida KT2440

NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
crp	yhfA	PP_0424	PP_0425	DNA-binding transcriptional dual regulator; Function experimentally demonstrated in the studied species; regulator; Transcription.	Homologs of previously reported genes of unknown function; Unknown function.	0.745
dsbA	yhfA	PP_0127	PP_0425	Thiol:disulfide interchange protein; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Proteinfate : Protein folding and stabilization.	Homologs of previously reported genes of unknown function; Unknown function.	0.445
ffh	hisG	PP_1461	PP_0965	GTPase component of the signal recognition particle (SRP); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into t [...]	ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily.	0.476
ffh	ttgB	PP_1461	PP_1385	GTPase component of the signal recognition particle (SRP); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into t [...]	Probable efflux pump membrane transporter TtgB; Probable membrane transporter component of the TtgABC efflux pump with unknown specificity; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.	0.463
ffh	yhfA	PP_1461	PP_0425	GTPase component of the signal recognition particle (SRP); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into t [...]	Homologs of previously reported genes of unknown function; Unknown function.	0.727
hisG	ffh	PP_0965	PP_1461	ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily.	GTPase component of the signal recognition particle (SRP); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into t [...]	0.476
hisG	yhfA	PP_0965	PP_0425	ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily.	Homologs of previously reported genes of unknown function; Unknown function.	0.416
ilvE	yhfA	PP_3511	PP_0425	Branched-chain-amino-acid aminotransferase.	Homologs of previously reported genes of unknown function; Unknown function.	0.408
ttgB	ffh	PP_1385	PP_1461	Probable efflux pump membrane transporter TtgB; Probable membrane transporter component of the TtgABC efflux pump with unknown specificity; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.	GTPase component of the signal recognition particle (SRP); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into t [...]	0.463
ttgB	yhfA	PP_1385	PP_0425	Probable efflux pump membrane transporter TtgB; Probable membrane transporter component of the TtgABC efflux pump with unknown specificity; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.	Homologs of previously reported genes of unknown function; Unknown function.	0.472
yhfA	crp	PP_0425	PP_0424	Homologs of previously reported genes of unknown function; Unknown function.	DNA-binding transcriptional dual regulator; Function experimentally demonstrated in the studied species; regulator; Transcription.	0.745
yhfA	dsbA	PP_0425	PP_0127	Homologs of previously reported genes of unknown function; Unknown function.	Thiol:disulfide interchange protein; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Proteinfate : Protein folding and stabilization.	0.445
yhfA	ffh	PP_0425	PP_1461	Homologs of previously reported genes of unknown function; Unknown function.	GTPase component of the signal recognition particle (SRP); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into t [...]	0.727
yhfA	hisG	PP_0425	PP_0965	Homologs of previously reported genes of unknown function; Unknown function.	ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily.	0.416
yhfA	ilvE	PP_0425	PP_3511	Homologs of previously reported genes of unknown function; Unknown function.	Branched-chain-amino-acid aminotransferase.	0.408
yhfA	ttgB	PP_0425	PP_1385	Homologs of previously reported genes of unknown function; Unknown function.	Probable efflux pump membrane transporter TtgB; Probable membrane transporter component of the TtgABC efflux pump with unknown specificity; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.	0.472