Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
coq2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6- methoxy-1,4-benzoquinol during ubiquinone biosynthesis. (215 aa)    
Predicted Functional Partners:
ubiG
Ubiquinone biosynthesis O-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
  
 0.995
ubiH
2-octaprenyl-6-methoxyphenyl hydroxylase.
  
 0.988
aroP-I
Aromatic amino acid transport protein; Function of homologous gene experimentally demonstrated in an other organism; transporter; Aminoacidbiosynthesis : Aromatic amino acid family.
      
 0.970
ubiE
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2).
   
 
 0.942
PP_1437
Heavy metal sensor histidine kinase; Member of a two-component regulatory system.
      
 0.895
aroP-II
Aromatic amino acid transport protein; Function of homologous gene experimentally demonstrated in an other organism; transporter; Aminoacidbiosynthesis : Aromatic amino acid family.
      
 0.861
ubiB
2-octaprenylphenol hydroxylase; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
   
 0.849
PP_0426
Homologs of previously reported genes of unknown function; putative membrane component; Unknown function.
  
    0.831
hinT
Aminoacyl-adenylate hydrolase/purine nucleoside phosphoramidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Biologicalprocesses : Maintain.
       0.775
visC
Putative oxidoreductase involved in anerobic synthesis of ubiquinone, FAD/NAD(P)-binding domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
 0.671
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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