| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PP_2213 | acsA-I | PP_2213 | PP_4487 | Putative acyl-CoA synthetase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.924 |
| PP_2213 | acsA-II | PP_2213 | PP_4702 | Putative acyl-CoA synthetase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.923 |
| PP_2213 | aldB-I | PP_2213 | PP_0545 | Putative acyl-CoA synthetase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Aldehyde dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energy metabolism; Belongs to the aldehyde dehydrogenase family. | 0.915 |
| PP_2213 | scpC | PP_2213 | PP_0154 | Putative acyl-CoA synthetase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | propionyl-CoA:succinate CoA transferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Central intermediary metabolism. | 0.964 |
| acsA-I | PP_2213 | PP_4487 | PP_2213 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Putative acyl-CoA synthetase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.924 |
| acsA-I | acsA-II | PP_4487 | PP_4702 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.902 |
| acsA-I | aldB-I | PP_4487 | PP_0545 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Aldehyde dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energy metabolism; Belongs to the aldehyde dehydrogenase family. | 0.923 |
| acsA-I | scpC | PP_4487 | PP_0154 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | propionyl-CoA:succinate CoA transferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Central intermediary metabolism. | 0.978 |
| acsA-II | PP_2213 | PP_4702 | PP_2213 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Putative acyl-CoA synthetase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.923 |
| acsA-II | acsA-I | PP_4702 | PP_4487 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.902 |
| acsA-II | aldB-I | PP_4702 | PP_0545 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Aldehyde dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energy metabolism; Belongs to the aldehyde dehydrogenase family. | 0.914 |
| acsA-II | scpC | PP_4702 | PP_0154 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | propionyl-CoA:succinate CoA transferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Central intermediary metabolism. | 0.952 |
| adhB | adhP | PP_3623 | PP_3839 | Alcohol dehydrogenase cytochrome c subunit. | Short-chain alcohol dehydrogenase; Function experimentally demonstrated in the studied genus; enzyme; Energymetabolism : Anaerobic. | 0.925 |
| adhB | aldB-I | PP_3623 | PP_0545 | Alcohol dehydrogenase cytochrome c subunit. | Aldehyde dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energy metabolism; Belongs to the aldehyde dehydrogenase family. | 0.916 |
| adhB | calA | PP_3623 | PP_2426 | Alcohol dehydrogenase cytochrome c subunit. | Coniferyl alcohol dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Fattyacidandphospholipidmetabolism : Degradation. | 0.912 |
| adhB | frmA | PP_3623 | PP_1616 | Alcohol dehydrogenase cytochrome c subunit. | Formaldehyde dehydrogenase, glutathione-dependent; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Fermentation. | 0.904 |
| adhB | qedH-I | PP_3623 | PP_2674 | Alcohol dehydrogenase cytochrome c subunit. | Quinoprotein ethanol dehydrogenase; Function experimentally demonstrated in the studied species; enzyme; Energy metabolism. | 0.918 |
| adhB | qedH-II | PP_3623 | PP_2679 | Alcohol dehydrogenase cytochrome c subunit. | Quinoprotein ethanol dehydrogenase; Function experimentally demonstrated in the studied species; enzyme; Energy metabolism. | 0.918 |
| adhP | adhB | PP_3839 | PP_3623 | Short-chain alcohol dehydrogenase; Function experimentally demonstrated in the studied genus; enzyme; Energymetabolism : Anaerobic. | Alcohol dehydrogenase cytochrome c subunit. | 0.925 |
| adhP | aldB-I | PP_3839 | PP_0545 | Short-chain alcohol dehydrogenase; Function experimentally demonstrated in the studied genus; enzyme; Energymetabolism : Anaerobic. | Aldehyde dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energy metabolism; Belongs to the aldehyde dehydrogenase family. | 0.914 |
