Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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dsbD-IThiol/disulfide interchange protein 1; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily. (590 aa)    
Predicted Functional Partners:
dsbC
Thiol:disulfide interchange protein DsbC; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily.
  
 
 0.949
dsbG
Periplasmic protein disulfide isomerase; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily.
  
 
 0.926
dsbB
Disulfide bond formation protein B; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity). Belongs to the DsbB family.
   
  
 0.830
ccmG
Holocytochrome c synthetase subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Electron transport.
  
 
 0.803
oruR
Transcriptional regulator, ornithine utilization; Function experimentally demonstrated in the studied genus; regulator.
      
 0.768
PP_4236
Putative Thiol:disulfide interchange protein dsbE; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
 
 0.717
PP_1646
Putative Thioredoxin; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
 
 0.675
PP_1832
Putative Oxidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
   
  
 0.661
PP_2405
Homologs of previously reported genes of unknown function.
  
 
 0.655
PP_4096
Homologs of previously reported genes of unknown function.
  
 
 0.631
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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