| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PP_0591 | PP_0747 | PP_0591 | PP_0747 | Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. | Hypoxanthine-guanine phosphoribosyltransferase. | 0.923 |
| PP_0591 | amn | PP_0591 | PP_4779 | Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. | AMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations. | 0.948 |
| PP_0591 | apt | PP_0591 | PP_4266 | Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.947 |
| PP_0591 | paoA | PP_0591 | PP_3308 | Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. | Promiscuous aromatic aldehyde dehydrogenase, 2Fe-2S subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.901 |
| PP_0591 | paoB | PP_0591 | PP_3309 | Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. | Promiscuous aromatic aldehyde dehydrogenase, FAD-binding subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Unknownfunction : Enzymes of unknown specificity. | 0.906 |
| PP_0591 | paoC | PP_0591 | PP_3310 | Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. | Promiscuous aromatic aldehyde dehydrogenase, molybdopterin-binding subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.902 |
| PP_0591 | ppnP | PP_0591 | PP_4248 | Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. | Conserved protein of unknown function, UPF0345 family; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. | 0.910 |
| PP_0591 | xdhA | PP_0591 | PP_4278 | Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. | Xanthine dehydrogenase subunit XdhA; Function experimentally demonstrated in the studied species; enzyme; Fattyacidandphospholipidmetabolism : Degradation. | 0.914 |
| PP_0591 | xdhB | PP_0591 | PP_4279 | Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. | Xanthine dehydrogenase subunit XdhB; Function experimentally demonstrated in the studied species; enzyme; Fattyacidandphospholipidmetabolism : Degradation. | 0.933 |
| PP_0591 | yfiH | PP_0591 | PP_0624 | Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. | Uncharacterized protein YfiH; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Unknown function; Belongs to the multicopper oxidase YfiH/RL5 family. | 0.903 |
| PP_0747 | PP_0591 | PP_0747 | PP_0591 | Hypoxanthine-guanine phosphoribosyltransferase. | Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. | 0.923 |
| PP_0747 | apt | PP_0747 | PP_4266 | Hypoxanthine-guanine phosphoribosyltransferase. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.853 |
| PP_0747 | paoA | PP_0747 | PP_3308 | Hypoxanthine-guanine phosphoribosyltransferase. | Promiscuous aromatic aldehyde dehydrogenase, 2Fe-2S subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.900 |
| PP_0747 | paoB | PP_0747 | PP_3309 | Hypoxanthine-guanine phosphoribosyltransferase. | Promiscuous aromatic aldehyde dehydrogenase, FAD-binding subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Unknownfunction : Enzymes of unknown specificity. | 0.900 |
| PP_0747 | paoC | PP_0747 | PP_3310 | Hypoxanthine-guanine phosphoribosyltransferase. | Promiscuous aromatic aldehyde dehydrogenase, molybdopterin-binding subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.900 |
| PP_0747 | ppnP | PP_0747 | PP_4248 | Hypoxanthine-guanine phosphoribosyltransferase. | Conserved protein of unknown function, UPF0345 family; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. | 0.900 |
| PP_0747 | xdhA | PP_0747 | PP_4278 | Hypoxanthine-guanine phosphoribosyltransferase. | Xanthine dehydrogenase subunit XdhA; Function experimentally demonstrated in the studied species; enzyme; Fattyacidandphospholipidmetabolism : Degradation. | 0.900 |
| PP_0747 | xdhB | PP_0747 | PP_4279 | Hypoxanthine-guanine phosphoribosyltransferase. | Xanthine dehydrogenase subunit XdhB; Function experimentally demonstrated in the studied species; enzyme; Fattyacidandphospholipidmetabolism : Degradation. | 0.912 |
| PP_0747 | yfiH | PP_0747 | PP_0624 | Hypoxanthine-guanine phosphoribosyltransferase. | Uncharacterized protein YfiH; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Unknown function; Belongs to the multicopper oxidase YfiH/RL5 family. | 0.924 |
| amn | PP_0591 | PP_4779 | PP_0591 | AMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations. | Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. | 0.948 |