STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PP_0591Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. (315 aa)    
Predicted Functional Partners:
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
 0.944
xdhB
Xanthine dehydrogenase subunit XdhB; Function experimentally demonstrated in the studied species; enzyme; Fattyacidandphospholipidmetabolism : Degradation.
 
  
 0.937
PP_0747
Hypoxanthine-guanine phosphoribosyltransferase.
   
 
 0.932
Nuh
Ribonucleoside hydrolase; Function experimentally demonstrated in the studied strain; enzyme; Purines,pyrimidines,nucleosides,andnucleotides : Nucleotide and nucleoside interconversions; Belongs to the IUNH family.
 
 
 0.932
amn
AMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.
  
 
 0.931
xdhA
Xanthine dehydrogenase subunit XdhA; Function experimentally demonstrated in the studied species; enzyme; Fattyacidandphospholipidmetabolism : Degradation.
    
 0.916
paoB
Promiscuous aromatic aldehyde dehydrogenase, FAD-binding subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Unknownfunction : Enzymes of unknown specificity.
    
  0.906
ppnP
Conserved protein of unknown function, UPF0345 family; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.
     
 0.904
paoC
Promiscuous aromatic aldehyde dehydrogenase, molybdopterin-binding subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
    
  0.903
paoA
Promiscuous aromatic aldehyde dehydrogenase, 2Fe-2S subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
    
  0.901
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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