STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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PP_0591Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. (315 aa)    
Predicted Functional Partners:
amn
AMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.
 
 
 0.948
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
 0.947
xdhB
Xanthine dehydrogenase subunit XdhB; Function experimentally demonstrated in the studied species; enzyme; Fattyacidandphospholipidmetabolism : Degradation.
 
  
 0.933
PP_0747
Hypoxanthine-guanine phosphoribosyltransferase.
     
 0.923
xdhA
Xanthine dehydrogenase subunit XdhA; Function experimentally demonstrated in the studied species; enzyme; Fattyacidandphospholipidmetabolism : Degradation.
    
 0.914
ppnP
Conserved protein of unknown function, UPF0345 family; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.
     
 0.910
paoB
Promiscuous aromatic aldehyde dehydrogenase, FAD-binding subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Unknownfunction : Enzymes of unknown specificity.
    
  0.906
yfiH
Uncharacterized protein YfiH; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Unknown function; Belongs to the multicopper oxidase YfiH/RL5 family.
    
  0.903
paoC
Promiscuous aromatic aldehyde dehydrogenase, molybdopterin-binding subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
    
  0.902
paoA
Promiscuous aromatic aldehyde dehydrogenase, 2Fe-2S subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
    
  0.901
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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