Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
PP_0596Omega-amino acid--pyruvate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (448 aa)    
Predicted Functional Partners:
mmsA-I
Methylmalonate-semialdehyde dehydrogenase; Function of strongly homologous gene; enzyme.
 
 0.979
prpE
propionyl-CoA synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energy metabolism.
     
 0.970
mmsA-II
Methylmalonate-semialdehyde dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Biologicalprocesses : Scavenge (Catabolism).
 
 
 0.941
PP_0614
Putative N-carbamoyl-beta-alanine amidohydrolase/allantoine amidohydrolase 1; Function experimentally demonstrated in the studied species; putative enzyme; Fattyacidandphospholipidmetabolism : Degradation.
 
 
  0.921
hyuC
N-carbamoyl-beta-alanine amidohydrolase/allantoine amidohydrolase 2; Function experimentally demonstrated in the studied species; enzyme; Fattyacidandphospholipidmetabolism : Degradation.
 
 
  0.921
panC
Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
   
 
 0.913
mmsB
3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family.
     
  0.900
PP_0595
Transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.
 
   
 0.840
bioB
Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.
 
  
 0.829
ydfG
3-hydroxy acid dehydrogenase, NADP-dependent / malonic semialdehyde reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Amino acids and amines.
      
 0.820
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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