thiO protein (Pseudomonas putida KT2440) - STRING interaction network

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thiO

FAD-dependent glycine/D-amino acid oxidase; Catalyzes the oxidation of glycine, leading to glyoxyl imine and hydrogen peroxide as primary products; glyoxyl imine is used for the biosynthesis of the thiazole ring of thiamine. Otherwise, glyoxyl imine is spontaneously hydrolyzed in water to produce glyoxylate and ammonia. Can also use sarcosine (N-methylglycine) as substrate, and, to a lesser extent, N-ethylglycine and D-proline. Has no activity towards other amino-acids D-Asp, D-Glu, D-Gln, D-His, D-Leu, D-Lys, D- ornithine, D-Trp, D-Val, L-Ala, L-Asp, L-Glu, L-His, L-Leu, L-Lys, L- Met [...] (365 aa)

Predicted Functional Partners:

thiG

0.999

pilE

0.908

ooxA

0.889

thiD

0.854

PP_0609

0.784

PP_0610

0.784

phnE

0.703

PP_0608

0.633

soxA

0.613

PP_5105

0.609

Your Current Organism:

Pseudomonas putida KT2440

NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PP_0608	PP_0609	PP_0608	PP_0609	Putative type 4 fimbrial biogenesis protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative structure.	Homologs of previously reported genes of unknown function.	0.976
PP_0608	PP_0610	PP_0608	PP_0610	Putative type 4 fimbrial biogenesis protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative structure.	Homologs of previously reported genes of unknown function.	0.964
PP_0608	pilE	PP_0608	PP_0611	Putative type 4 fimbrial biogenesis protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative structure.	Type IV pili biogenesis protein PilE.	0.960
PP_0608	thiO	PP_0608	PP_0612	Putative type 4 fimbrial biogenesis protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative structure.	FAD-dependent glycine/D-amino acid oxidase; Catalyzes the oxidation of glycine, leading to glyoxyl imine and hydrogen peroxide as primary products; glyoxyl imine is used for the biosynthesis of the thiazole ring of thiamine. Otherwise, glyoxyl imine is spontaneously hydrolyzed in water to produce glyoxylate and ammonia. Can also use sarcosine (N-methylglycine) as substrate, and, to a lesser extent, N-ethylglycine and D-proline. Has no activity towards other amino-acids D-Asp, D-Glu, D-Gln, D-His, D-Leu, D-Lys, D- ornithine, D-Trp, D-Val, L-Ala, L-Asp, L-Glu, L-His, L-Leu, L-Lys, L- Met [...]	0.633
PP_0609	PP_0608	PP_0609	PP_0608	Homologs of previously reported genes of unknown function.	Putative type 4 fimbrial biogenesis protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative structure.	0.976
PP_0609	PP_0610	PP_0609	PP_0610	Homologs of previously reported genes of unknown function.	Homologs of previously reported genes of unknown function.	0.982
PP_0609	pilE	PP_0609	PP_0611	Homologs of previously reported genes of unknown function.	Type IV pili biogenesis protein PilE.	0.984
PP_0609	thiO	PP_0609	PP_0612	Homologs of previously reported genes of unknown function.	FAD-dependent glycine/D-amino acid oxidase; Catalyzes the oxidation of glycine, leading to glyoxyl imine and hydrogen peroxide as primary products; glyoxyl imine is used for the biosynthesis of the thiazole ring of thiamine. Otherwise, glyoxyl imine is spontaneously hydrolyzed in water to produce glyoxylate and ammonia. Can also use sarcosine (N-methylglycine) as substrate, and, to a lesser extent, N-ethylglycine and D-proline. Has no activity towards other amino-acids D-Asp, D-Glu, D-Gln, D-His, D-Leu, D-Lys, D- ornithine, D-Trp, D-Val, L-Ala, L-Asp, L-Glu, L-His, L-Leu, L-Lys, L- Met [...]	0.784
PP_0610	PP_0608	PP_0610	PP_0608	Homologs of previously reported genes of unknown function.	Putative type 4 fimbrial biogenesis protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative structure.	0.964
PP_0610	PP_0609	PP_0610	PP_0609	Homologs of previously reported genes of unknown function.	Homologs of previously reported genes of unknown function.	0.982
PP_0610	pilE	PP_0610	PP_0611	Homologs of previously reported genes of unknown function.	Type IV pili biogenesis protein PilE.	0.963
PP_0610	thiO	PP_0610	PP_0612	Homologs of previously reported genes of unknown function.	FAD-dependent glycine/D-amino acid oxidase; Catalyzes the oxidation of glycine, leading to glyoxyl imine and hydrogen peroxide as primary products; glyoxyl imine is used for the biosynthesis of the thiazole ring of thiamine. Otherwise, glyoxyl imine is spontaneously hydrolyzed in water to produce glyoxylate and ammonia. Can also use sarcosine (N-methylglycine) as substrate, and, to a lesser extent, N-ethylglycine and D-proline. Has no activity towards other amino-acids D-Asp, D-Glu, D-Gln, D-His, D-Leu, D-Lys, D- ornithine, D-Trp, D-Val, L-Ala, L-Asp, L-Glu, L-His, L-Leu, L-Lys, L- Met [...]	0.784
PP_5105	thiD	PP_5105	PP_4782	Sulfur carrier protein ThiS.	Phosphomethylpyrimidine kinase.	0.912
PP_5105	thiG	PP_5105	PP_5104	Sulfur carrier protein ThiS.	Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.	0.998
PP_5105	thiO	PP_5105	PP_0612	Sulfur carrier protein ThiS.	FAD-dependent glycine/D-amino acid oxidase; Catalyzes the oxidation of glycine, leading to glyoxyl imine and hydrogen peroxide as primary products; glyoxyl imine is used for the biosynthesis of the thiazole ring of thiamine. Otherwise, glyoxyl imine is spontaneously hydrolyzed in water to produce glyoxylate and ammonia. Can also use sarcosine (N-methylglycine) as substrate, and, to a lesser extent, N-ethylglycine and D-proline. Has no activity towards other amino-acids D-Asp, D-Glu, D-Gln, D-His, D-Leu, D-Lys, D- ornithine, D-Trp, D-Val, L-Ala, L-Asp, L-Glu, L-His, L-Leu, L-Lys, L- Met [...]	0.609
ooxA	thiO	PP_4456	PP_0612	Opine oxidase subunit A; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Amino acids and amines.	FAD-dependent glycine/D-amino acid oxidase; Catalyzes the oxidation of glycine, leading to glyoxyl imine and hydrogen peroxide as primary products; glyoxyl imine is used for the biosynthesis of the thiazole ring of thiamine. Otherwise, glyoxyl imine is spontaneously hydrolyzed in water to produce glyoxylate and ammonia. Can also use sarcosine (N-methylglycine) as substrate, and, to a lesser extent, N-ethylglycine and D-proline. Has no activity towards other amino-acids D-Asp, D-Glu, D-Gln, D-His, D-Leu, D-Lys, D- ornithine, D-Trp, D-Val, L-Ala, L-Asp, L-Glu, L-His, L-Leu, L-Lys, L- Met [...]	0.889
phnE	thiO	PP_0826	PP_0612	Phosphonate ABC transporter, permease protein; Function experimentally demonstrated in the studied genus; transporter.	FAD-dependent glycine/D-amino acid oxidase; Catalyzes the oxidation of glycine, leading to glyoxyl imine and hydrogen peroxide as primary products; glyoxyl imine is used for the biosynthesis of the thiazole ring of thiamine. Otherwise, glyoxyl imine is spontaneously hydrolyzed in water to produce glyoxylate and ammonia. Can also use sarcosine (N-methylglycine) as substrate, and, to a lesser extent, N-ethylglycine and D-proline. Has no activity towards other amino-acids D-Asp, D-Glu, D-Gln, D-His, D-Leu, D-Lys, D- ornithine, D-Trp, D-Val, L-Ala, L-Asp, L-Glu, L-His, L-Leu, L-Lys, L- Met [...]	0.703
pilE	PP_0608	PP_0611	PP_0608	Type IV pili biogenesis protein PilE.	Putative type 4 fimbrial biogenesis protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative structure.	0.960
pilE	PP_0609	PP_0611	PP_0609	Type IV pili biogenesis protein PilE.	Homologs of previously reported genes of unknown function.	0.984
pilE	PP_0610	PP_0611	PP_0610	Type IV pili biogenesis protein PilE.	Homologs of previously reported genes of unknown function.	0.963

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