Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
yfiHUncharacterized protein YfiH; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Unknown function; Belongs to the multicopper oxidase YfiH/RL5 family. (246 aa)    
Predicted Functional Partners:
rluD
23S rRNA pseudouridine(1911,1915,1917) synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.
 
  
 0.947
PP_0747
Hypoxanthine-guanine phosphoribosyltransferase.
  
 
  0.924
PP_2531
Putative 5-nucleotidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
  
  0.916
PP_3254
Putative Nucleosidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
    
 0.907
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
    
  0.905
xpt
Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
    
  0.905
PP_0591
Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.
    
  0.903
paoC
Promiscuous aromatic aldehyde dehydrogenase, molybdopterin-binding subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
    
  0.903
PP_3662
Homologs of previously reported genes of unknown function; Unknown function.
     
 0.903
amn
AMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.
    
 0.903
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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