STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pilAFimbrial protein; Belongs to the N-Me-Phe pilin family. (136 aa)    
Predicted Functional Partners:
pilD
Leader peptidase/N-methyltransferase; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.
 
   
 0.839
pilC
Type 4 fimbrial assembly protein PilC.
 
  
 0.823
pilQ
Type 4 pili biogenesis protein; Function of strongly homologous gene; structure; Cell envelope.
 
   
 0.787
PP_5083
Putative Type IV pili biogenesis protein PilM; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
   
 0.774
pilE
Type IV pili biogenesis protein PilE.
 
  
 0.719
pilT
Twitching motility protein; Function experimentally demonstrated in the studied genus; cell process.
 
   
 0.633
pilN
Type IV pili biogenesis protein PilN.
  
   
 0.604
yacG
DNA gyrase inhibitor YacG; Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C- terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
  
    0.568
coaE
Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
  
    0.564
PP_5190
Type II secretion system protein.
 
  
 0.553
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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