STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PP_0693Homologs of previously reported genes of unknown function. (943 aa)    
Predicted Functional Partners:
sbcD
Exonuclease SbcD; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
  
 0.971
polA
DNA polymerase I, 5' -> 3' polymerase with 5' --> 3' and 3' --> 5' exonuclease activity; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.947
PP_0694
Homologs of previously reported genes of unknown function.
  
  
 0.846
PP_2565
Putative helicase, UvrD/REP family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; DNA metabolism.
 
 
 0.816
PP_0695
Homologs of previously reported genes of unknown function.
       0.807
PP_3399
Minor curlin subunit CsgB, nucleation component of curlin monomers; Function of strongly homologous gene; factor; Cell envelope.
  
     0.771
PP_2566
Conserved protein of unknown function containing Leucine-rich repeat domain; Homologs of previously reported genes of unknown function; Unknown function.
  
    0.763
recQ
ATP-dependent DNA 3' to 5' helicase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; DNA metabolism.
  
 0.763
PP_4775
Homologs of previously reported genes of unknown function; Unknown function.
  
    0.749
PP_1072
Leucine-rich repeat domain protein.
  
    0.743
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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