STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PP_0705DNA-3-methyladenine glycosylase. (208 aa)    
Predicted Functional Partners:
ada
Fused O(6)-alkylguanine DNA alkyltransferase - transcriptional activator; Function of homologous gene experimentally demonstrated in an other organism; enzyme; DNAmetabolism : DNA replication, recombination, and repair.
  
  
 0.988
ogt
O6-methylguanine-DNA methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
 
  
 0.962
alkB
Alpha-ketoglutarate- and Fe(II)-dependent dioxygenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; DNAmetabolism : Restriction/modification.
     
 0.850
gpD
Pyocin R2_PP, tail formation.
      
 0.676
PP_2707
Putative Exodeoxyribonuclease III; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
 0.634
xthA
Exodeoxyribonuclease III / apurinic/apyrimidinic endodeoxyribonuclease VI; Function of homologous gene experimentally demonstrated in an other organism; enzyme; DNAmetabolism : Degradation of DNA.
  
 0.634
PP_5292
Catabolite repression control protein.
  
 0.634
polA
DNA polymerase I, 5' -> 3' polymerase with 5' --> 3' and 3' --> 5' exonuclease activity; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
 
 0.580
PP_0703
Putative Transmembrane sensor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
       0.512
PP_0704
RNA polymerase sigma-70 factor, ECF subfamily.
       0.512
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.