Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PP_0705DNA-3-methyladenine glycosylase. (208 aa)    
Predicted Functional Partners:
ada
Fused O(6)-alkylguanine DNA alkyltransferase - transcriptional activator; Function of homologous gene experimentally demonstrated in an other organism; enzyme; DNAmetabolism : DNA replication, recombination, and repair.
  
  
 0.996
ogt
O6-methylguanine-DNA methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
 
  
 0.967
alkB
Alpha-ketoglutarate- and Fe(II)-dependent dioxygenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; DNAmetabolism : Restriction/modification.
     
 0.855
gpD
Pyocin R2_PP, tail formation.
      
 0.818
imuB
DNA linked enzyme involved in DNA repair; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.594
recA
Protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
    
 
 0.541
polA
DNA polymerase I, 5' -> 3' polymerase with 5' --> 3' and 3' --> 5' exonuclease activity; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
 
 0.525
PP_0707
Putative membrane protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
     
 0.514
PP_0703
Putative Transmembrane sensor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
       0.512
PP_0704
RNA polymerase sigma-70 factor, ECF subfamily.
       0.512
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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