Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PP_0716HlyD family secretion protein. (365 aa)    
Predicted Functional Partners:
PP_0715
Outer membrane efflux protein.
 
   0.917
PP_0714
Transporter, PerM family.
 
    0.906
PP_0717
Conserved membrane protein of unknown function, DUF2955 family; Homologs of previously reported genes of unknown function; Unknown function.
       0.793
PP_1975
Putative EmrB/QacA family drug resistance transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the major facilitator superfamily.
  
 
 0.656
kefB-I
Kef-type potassium/proton antiporter, CPA2 family; Function of homologous gene experimentally demonstrated in an other organism; transporter; Transportandbindingproteins : Cations and iron carrying compounds; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
       0.639
PP_2067
Putative EmrB/QacA family drug resistance transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the major facilitator superfamily.
  
 
 0.629
ppkB
Polyphosphate kinase 2; Function experimentally demonstrated in the studied genus; enzyme; Centralintermediarymetabolism : Phosphorus compounds.
 
    0.606
pvdT
Pyoverdine efflux carrier and ATP binding protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
  
 0.592
emrB
Multidrug efflux transport system - permease subunit; Function of homologous gene experimentally demonstrated in an other organism; transporter; Transport and binding proteins; Belongs to the major facilitator superfamily.
  
 
 0.590
paxB
Toxin secretion ATP-binding protein.
 
 
 0.520
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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