STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PP_0740Transcriptional regulator, MerR family. (299 aa)    
Predicted Functional Partners:
PP_0741
Homologs of previously reported genes of unknown function; Unknown function.
 
  
 0.954
phr
Deoxyribodipyrimidine photolyase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Biosynthesisofcofactors,prostheticgroups,andcarriers : Riboflavin, FMN, and FAD; Belongs to the DNA photolyase family.
  
  
 0.900
czcR-I
Two component heavy metal response regulator; Function of strongly homologous gene; regulator; Biologicalprocesses : Control.
    
 
 0.845
czcR-II
Response regulator; Function experimentally demonstrated in the studied genus; regulator; Biologicalprocesses : Control.
    
 
 0.845
czcR-III
Response regulator; Function of strongly homologous gene; regulator; Biologicalprocesses : Control.
    
 
 0.845
PP_0742
Conserved exported protein of unknown function; Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P)+. May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers; Belongs to the bacterial renalase family.
      0.834
PP_0738
Homologs of previously reported genes of unknown function.
 
     0.828
PP_3262
Putative Metallothionein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
      
 0.753
czcC
Metal RND efflux outer membrane protein, CzcC family; Function experimentally demonstrated in the studied genus; factor; Biologicalprocesses : Excrete.
      
 0.647
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
  
 
 0.493
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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