STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hprAGlycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (321 aa)    
Predicted Functional Partners:
glcE
Glycolate oxidase, putative FAD-binding subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Central intermediary metabolism.
 
 
 0.927
ttuD
Putative hydroxypyruvate reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
 0.927
ghrB
2-ketoaldonate reductase / hydroxypyruvate/glyoxylate reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Sugars; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
  
 
0.925
glcD
Glycolate oxidase, putative FAD-linked subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energy metabolism.
 
 
 0.925
garK
Glycerate kinase; Function experimentally demonstrated in the studied strain; enzyme; Energymetabolism : Sugars; Belongs to the glycerate kinase type-1 family.
 
  
 0.921
glcB
Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.
   
 
 0.913
PP_0416
Phosphoglycolate phosphatase; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
 
  
  0.913
hyi
Hydroxypyruvate isomerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Central intermediary metabolism; Belongs to the hyi family.
   
 
 0.908
aceA
Isocitrate lyase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : TCA cycle.
     
 0.906
glcF
Glycolate oxidase, iron-sulfur subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energy metabolism.
    
 0.905
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.