Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hprAGlycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (321 aa)    
Predicted Functional Partners:
ghrB
2-ketoaldonate reductase / hydroxypyruvate/glyoxylate reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Sugars; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
  
 
0.925
glcE
Glycolate oxidase, putative FAD-binding subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Central intermediary metabolism.
 
 
 0.925
glcD
Glycolate oxidase, putative FAD-linked subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energy metabolism.
 
 
 0.923
ttuD
Putative hydroxypyruvate reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
 
 0.923
garK
Glycerate kinase; Function experimentally demonstrated in the studied strain; enzyme; Energymetabolism : Sugars; Belongs to the glycerate kinase type-1 family.
 
  
 0.921
PP_0416
Phosphoglycolate phosphatase; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
 
  
  0.913
glcB
Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.
  
 
 0.910
PP_0094
5'-nucleotidase.
  
 
  0.906
hyi
Hydroxypyruvate isomerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Central intermediary metabolism; Belongs to the hyi family.
   
 
 0.906
aceA
Isocitrate lyase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : TCA cycle.
     
 0.905
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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