Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cysZPutative cysZ protein, required for sulfate transport; High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway; Belongs to the CysZ family. (242 aa)    
Predicted Functional Partners:
PP_4289
Homologs of previously reported genes of unknown function.
      
 0.744
rarD
Chloramphenicol-sensitive protein; Function of strongly homologous gene; transporter.
      
 0.584
PP_1126
Putative Hydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
      
 0.575
PP_5344
Acetyltransferase.
      
 0.558
PP_3338
Putative cytochrome bd-type quinol oxidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Energy metabolism.
      
 0.543
PP_0188
Putative Uroporphyrin-III C-methyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
     0.537
trxB
Thioredoxin reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Central intermediary metabolism.
       0.519
zipA
Putative cell division protein ZipA; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.
 
     0.517
rmf
Ribosome modulation factor; During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes); Belongs to the ribosome modulation factor family.
  
   
 0.499
tsaA
Putative peroxiredoxin; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
       0.474
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
Server load: low (8%) [HD]