STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fruAFructose PTS permease - IIBC component; Function of homologous gene experimentally demonstrated in an other organism; transporter; Energy metabolism. (580 aa)    
Predicted Functional Partners:
fruB
Phosphotransferase system, fructose-specific EI/HPr/EIIA components; Function experimentally demonstrated in the studied genus; transporter; Energymetabolism : Sugars; Belongs to the PEP-utilizing enzyme family.
 
 
 0.999
fruK
1-phosphofructokinase monomer; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energy metabolism; Belongs to the carbohydrate kinase PfkB family.
 
 0.999
ptsN
Phosphotransferase system enzyme IIA, regulation of potassium transport; Function of homologous gene experimentally demonstrated in an other organism; regulator; Transportandbindingproteins : Carbohydrates, organic alcohols, and acids.
 
  
 0.995
fba
Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
  
 
 0.975
cra
Catabolite repressor-activator, DNA-binding transcriptional dual regulator; Function of homologous gene experimentally demonstrated in an other organism; regulator; Energymetabolism : Entner-Doudoroff.
 
   
 0.969
ptsP
Phosphoenolpyruvate-dependent regulator (with NPR and NTR proteins); Function of homologous gene experimentally demonstrated in an other organism; regulator; Energy metabolism; Belongs to the PEP-utilizing enzyme family.
  
   
 0.914
PP_5410
Transcriptional regulator, DeoR family.
 
  
 0.891
glpR
DNA-binding transcriptional repressor - GlpR-glycerol-3-phosphate; Function of homologous gene experimentally demonstrated in an other organism; regulator; Energymetabolism : Anaerobic.
 
  
 0.882
algD
GDP-mannose 6-dehydrogenase; Catalyzes the oxidation of guanosine diphospho-D-mannose (GDP-D-mannose) to GDP-D-mannuronic acid, a precursor for alginate polymerization. The alginate layer causes a mucoid phenotype and provides a protective barrier against host immune defenses and antibiotics (By similarity).
     
 0.802
PP_0728
Homologs of previously reported genes of unknown function.
  
  
 0.755
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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