STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
norRDNA-binding transcriptional dual regulator (NO); Function of homologous gene experimentally demonstrated in an other organism; regulator; Transcription. (518 aa)    
Predicted Functional Partners:
hmp
Flavohemoprotein; Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress; Belongs to the globin family. Two-domain flavohemoproteins subfamily.
 
   
 0.937
rpoN
RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of the xylCAB operon and the xylS gene. The open complex (sigma-54 and core RNA polymerase) serves as the receptor for receipt of the melting signal from the remotely bound activator protein XylR for the expression of the xylCAB operon and xylS.
 
   
 0.873
fnrB
Transcriptional regulator with 4Fe-4S cluster, Crp/Fnr family; Function experimentally demonstrated in the studied strain; regulator.
   
 
 0.715
fnrC
Transcriptional regulator with 4Fe-4S cluster; Function experimentally demonstrated in the studied strain; regulator.
   
 
 0.713
PP_2354
Sensory box histidine kinase/response regulator.
   
 
 0.584
ohrR
Organic hydroperoxide resistance transcriptional regulator.
   
  
 0.544
PP_3651
Sensor histidine kinase/response regulator.
   
 
 0.534
PP_1695
Putative Sodium-solute symporter/sensory box histidine kinase/response regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
 
 0.526
PP_5242
Sensor histidine kinase/GAF domain protein.
  
 
 0.500
PP_4203
Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone.
  
  
 0.474
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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