Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
norRDNA-binding transcriptional dual regulator (NO); Function of homologous gene experimentally demonstrated in an other organism; regulator; Transcription. (518 aa)    
Predicted Functional Partners:
hmp
Flavohemoprotein; Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress; Belongs to the globin family. Two-domain flavohemoproteins subfamily.
 
   
 0.964
rpoN
RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of the xylCAB operon and the xylS gene. The open complex (sigma-54 and core RNA polymerase) serves as the receptor for receipt of the melting signal from the remotely bound activator protein XylR for the expression of the xylCAB operon and xylS.
 
   
 0.859
PP_2354
Sensory box histidine kinase/response regulator.
   
 
 0.759
PP_3835
Sensory box histidine kinase.
   
 
 0.674
PP_0802
Putative chemotaxis protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative cell process.
   
 
 0.650
ohrR
Organic hydroperoxide resistance transcriptional regulator.
   
  
 0.640
PP_3651
Sensor histidine kinase/response regulator.
   
 
 0.619
gltB
L-glutamate synthase(NADPH) alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Aminoacidbiosynthesis : Glutamate family.
     
 0.593
PP_2840
Putative Membrane protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
     
 0.535
PP_2945
Putative sensor histidine kinase/response regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
   
 
 0.519
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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