STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hmpFlavohemoprotein; Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress; Belongs to the globin family. Two-domain flavohemoproteins subfamily. (392 aa)    
Predicted Functional Partners:
norR
DNA-binding transcriptional dual regulator (NO); Function of homologous gene experimentally demonstrated in an other organism; regulator; Transcription.
 
   
 0.937
PP_2129
Homologs of previously reported genes of unknown function.
      0.858
PP_2840
Putative Membrane protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
  
 0.809
PP_3175
Putative Dioxygenase, ferredoxin reductase component; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
  
 0.779
PP_5371
Rubredoxin/rubredoxin reductase; Belongs to the FAD-dependent oxidoreductase family.
  
  
 0.730
nirB
Nitrite reductase [NAD(P)H] large subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Anaerobic; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
  
  
 0.688
alkT
Rubredoxin-NAD(+) reductase; Belongs to the FAD-dependent oxidoreductase family.
  
  
 0.642
ahpF
Alkyl hydroperoxide reductase subunit F; Serves to protect the cell against DNA damage by alkyl hydroperoxides. It can use either NADH or NADPH as electron donor for direct reduction of redox dyes or of alkyl hydroperoxides when combined with the AhpC protein (By similarity); Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
      
 0.631
iscR
DNA-binding transcriptional dual regulator 2Fe-2S cluster IscR; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins.
  
  
 0.595
trxB
Thioredoxin reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Central intermediary metabolism.
      
 0.584
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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