STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hmpFlavohemoprotein; Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress; Belongs to the globin family. Two-domain flavohemoproteins subfamily. (392 aa)    
Predicted Functional Partners:
norR
DNA-binding transcriptional dual regulator (NO); Function of homologous gene experimentally demonstrated in an other organism; regulator; Transcription.
 
   
 0.964
PP_2129
Homologs of previously reported genes of unknown function.
      0.857
PP_2840
Putative Membrane protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
  
 0.856
PP_3175
Putative Dioxygenase, ferredoxin reductase component; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
  
 0.849
PP_5371
Rubredoxin/rubredoxin reductase; Belongs to the FAD-dependent oxidoreductase family.
  
  
 0.823
PP_0430
Homologs of previously reported genes of unknown function.
     
 0.809
yrpB
2-nitropropane dioxygenase; Function experimentally demonstrated in the studied genus; enzyme; Biologicalprocesses : Protect.
     
 0.795
ahpF
Alkyl hydroperoxide reductase subunit F; Serves to protect the cell against DNA damage by alkyl hydroperoxides. It can use either NADH or NADPH as electron donor for direct reduction of redox dyes or of alkyl hydroperoxides when combined with the AhpC protein (By similarity); Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
      
 0.679
sodA
Superoxide dismutase (Mn); Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
     
 0.659
nirB
Nitrite reductase [NAD(P)H] large subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Anaerobic; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
  
  
 0.644
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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