STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
alaCAminotransferase; Function of strongly homologous gene; enzyme; Regulatory functions. (402 aa)    
Predicted Functional Partners:
fucD
L-fuconate dehydratase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Pentose phosphate pathway; Belongs to the mandelate racemase/muconate lactonizing enzyme family.
     
 0.653
lldD
L-lactate dehydrogenase; Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain.
  
  
 0.651
panB
3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
  
  
 0.560
ilvE
Branched-chain-amino-acid aminotransferase.
  
  
 0.538
PP_0818
Homologs of previously reported genes of unknown function; Unknown function.
  
    0.524
tyrB
Aromatic-amino-acid aminotransferase; Function experimentally demonstrated in the studied strain; enzyme; Aminoacidbiosynthesis : Aspartate family.
   
 
 0.512
gltB
L-glutamate synthase(NADPH) alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Aminoacidbiosynthesis : Glutamate family.
     
 0.478
cyoE
Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
  
   0.475
cyoB
Cytochrome bo terminal oxidase subunit I; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Aerobic; Belongs to the heme-copper respiratory oxidase family.
   
 
 0.458
cyoD
Cytochrome bo terminal oxidase subunit IV; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Aerobic.
     
 0.456
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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