Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
selUtRNA 2-selenouridine synthase; Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2- selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain. (370 aa)    
Predicted Functional Partners:
selD
Selenide, water dikinase; Synthesizes selenophosphate from selenide and ATP.
   
 0.995
ptxB
Phosphonate transport system-binding protein; Function experimentally demonstrated in the studied genus; transporter; Centralintermediarymetabolism : Phosphorus compounds.
 
     0.716
phnC
Phosphonates import ATP-binding protein; Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family.
 
     0.671
phnE
Phosphonate ABC transporter, permease protein; Function experimentally demonstrated in the studied genus; transporter.
 
     0.665
selO
Conserved protein of unknown function, UPF0061 family; Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).
      
 0.584
ptxC
Putative phosphonate transport system permease protein PtxC; Function experimentally demonstrated in the studied genus; putative transporter; Centralintermediarymetabolism : Phosphorus compounds.
       0.563
selB
selenocysteyl-tRNA-specific translation elongation factor; Function of homologous gene experimentally demonstrated in an other organism; factor; Proteinsynthesis : Translation factors.
  
  
 0.552
selA
Selenocysteine synthase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
 
  
 0.538
PP_2305
Homologs of previously reported genes of unknown function.
       0.488
PP_2306
Homologs of previously reported genes of unknown function.
       0.488
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.