Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PP_0852Transcriptional regulator, Cro/CI family. (335 aa)    
Predicted Functional Partners:
smc
Chromosome partition protein Smc; Required for chromosome condensation and partitioning. Belongs to the SMC family.
     
 0.971
ispG
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family.
 
    0.957
pilF
Type IV pili biogenesis protein PilF.
 
    0.904
mreB
Cell wall structural actin-like protein MreB; Function of homologous gene experimentally demonstrated in an other organism; structure; Cellularprocesses : Cell division.
  
 
 0.898
hisS
Histidine--tRNA ligase.
 
    0.880
rlmN
Dual-specificity RNA methyltransferase RlmN; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family.
  
    0.875
PP_5057
Peptidase, M23/M37 family.
  
   
 0.861
PP_0855
Homologs of previously reported genes of unknown function.
 
    0.856
bamB
Conserved lipoprotein of unknown function; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
 
    0.831
pgsA
CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Fattyacidandphospholipidmetabolism : Biosynthesis; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
  
    0.828
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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