STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
speCOrnithine decarboxylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (387 aa)    
Predicted Functional Partners:
speB
Agmatinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Centralintermediarymetabolism : Polyamine biosynthesis; Belongs to the arginase family.
  
 
 0.921
PP_3190
Ornithine cyclodeaminase/mu-crystallin family protein.
  
 
 0.918
ocd-2
Putative ornithine cyclodeaminase; Catalyzes the conversion of L-ornithine into L-proline with release of ammonia. Is likely involved in the L-ornithine degradation pathway that allows P.putida to utilize this compound as sole carbon and nitrogen source.
  
 
 0.918
ocd
Ornithine cyclodeaminase 1.
  
 
 0.918
spuC-II
Polyamine:pyruvate transaminase; Function experimentally demonstrated in the studied genus; enzyme; Central intermediary metabolism; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
     
 0.904
prr
Gamma-aminobutyraldehyde dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the aldehyde dehydrogenase family.
      
 0.745
speA
Biosynthetic arginine decarboxylase; Catalyzes the biosynthesis of agmatine from arginine. Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
  
  
 0.733
PP_4523
Putative Agmatinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the arginase family.
  
 
 0.608
guaA
Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
  
 0.542
argA
Acetylglutamate kinase-like protein (regulatory domain)/amino acid N-acetyltransferase; Function experimentally demonstrated in the studied genus; enzyme.
  
  
 0.531
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.