STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PP_0893ThiJ/PfpI family protein. (195 aa)    
Predicted Functional Partners:
PP_3301
RND efflux membrane fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
      
 0.834
nth
DNA glycosylase/apyrimidinic (AP) lyase specific for damaged pyrimidinic sites; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
   
 
 0.768
PP_0892
Phospholipase family protein.
  
  
 0.655
PP_0891
Homologs of previously reported genes of unknown function; Belongs to the UPF0312 family.
  
    0.640
PP_0889
Homologs of previously reported genes of unknown function.
  
    0.524
PP_0890
Homologs of previously reported genes of unknown function.
  
    0.521
nuoC
NADH-quinone oxidoreductase subunit C/D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family.
  
 
 0.477
sdhB
Succinate dehydrogenase iron-sulfur subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Aerobic.
   
 
 0.423
PP_0887
Sensor histidine kinase.
       0.422
regA
Photosynthetic apparatus regulatory protein RegA.
       0.422
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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